Stages of Alzheimer's Disease
Misplacing
your car keys, calling your neighbor by the wrong name or forgetting to buy
bread at the grocery store are common memory lapses. But with age,
forgetfulness happens more often, and it’s easy to begin questioning what’s
normal — like if it’s a sign of Alzheimer’s disease.
Alzheimer’s
disease is the most common form of dementia, which is a term to describe the
loss of cognitive functioning. Over time, Alzheimer’s can lead to an inability
to carry out daily activities, such as getting dressed, having conversations.
If
someone you care about is experiencing signs of Alzheimer's, knowing the signs
of each stage can help you assist in managing the disease.
“There's
no cure for Alzheimer's,” explains David Wolk, MD, co-director of the Penn
Memory Center, “but there are medications that can keep the symptoms from
getting worse for a period of time.”
Remember,
Alzheimer’s affects everyone differently. The timing and severity may be
different for each person, and it can be difficult to determine which stage
your loved one is in because stages may overlap and are only meant to be a
guideline
Stage 1: Before Symptoms Appear
Just
like with many diseases, changes in the brain that are related to Alzheimer’s
begin before symptoms are noticeable.
“This
time period — often called ‘preclinical Alzheimer’s disease’ — likely begins 10
or 15 years before people have symptoms,” says Dr. Wolk. “Currently, there is
no treatment for this preclinical stage, but we hope in the future that we will
have medicines that can halt the progress before people have symptoms and
prevent the disease.”
Because
the risk of Alzheimer’s increases with age, it’s important to keep up with
regular primary care visits to allow for screening to detect the earliest signs
of disease. If you notice your loved one’s cognitive abilities beginning to
slip, that may mean they’re entering the second stage of Alzheimer’s disease.
Stage
2: Basic Forgetfulness
Everyone
can be forgetful from time to time, and that’s likely to happen more often with
age. Very early stages of Alzheimer’s can look like normal-aged forgetfulness.
Your
loved one might have memory lapses, including forgetting people’s names or
where they left their keys, but they can still drive, work and be social.
However, these memory lapses become more frequent. You will probably notice
this before your loved one does — and you may be able to get them treatment
sooner to slow the progression.
Stage
3: Noticeable Memory Difficulties
“For
many, this stage brings noticeable changes, and it will become harder to blame
age. It’s common to be diagnosed in this stage, because this is when a person’s
daily routine becomes more disrupted,” explains Dr. Wolk.
Common
difficulties in this stage go beyond forgetting names and misplacing objects.
Your loved one may:
Have
trouble remembering recently read material, such as books or magazines
Find
remember plans and organizing increasingly difficult
Have
more difficulty retrieving a name or word
Experience
challenges in social settings or at work
This
stage may bring about more anxiety for your loved one, and some people may even
deny that anything is wrong. These feelings are normal, but not talking to a
physician will only allow symptoms to get worse. The best way to keep symptoms
at bay is to talk to your loved one’s physician about treatment options,
including medications, and care planning.
Stage
4: More Than Memory Loss
“In
this stage, damage to the brain often involves other aspects of cognition
outside of memory, including some difficulty with language, organization, and
calculations. These problems can make it
more challenging for your loved one to perform daily tasks,” says Dr. Wolk.
During
this stage — which can last for many years — your loved one will experience
major difficulties with memory. They may still remember significant details
about their life, such as who they are married to or what state they live in.
Their memory of the distant past will usually be significantly better than
their memory of day-to-day information, such as what they saw on the news or a
conversation from earlier in the day.
Other
challenges during this stage include:
Confusion
about what day it is and where they are
Increased
risk of wandering off or getting lost
Changes
in sleep patterns, such as restlessness at night and sleeping during the day
Difficulty
choosing appropriate clothing for the weather or the occasion
During
this stage, situations that require a lot of thinking, such as being at a
social gathering, can be very frustrating, and it’s common to feel moody or
withdrawn.
“Because
of the damage to the brain cells, your loved one may also experience other
personality changes, such as feeling suspicious of others, having less interest
in things, or feeling depressed,” explains Dr. Wolk. “These kinds of symptoms
can often be improved with medications.”
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